The Bronco Discovery and Innovation Series is hosted by University Advancement in partnership with university leaders welcoming Boise State President’s Club members and guests to hear from the brightest minds in research today.
Spring 2018 Presentation
Unraveling the Mystery of the Greatest, Genetic Risk Factor for Alzheimer’s Disease
Presented by Troy Rohn
Date: Wednesday, March 7
Location: Alumni and Friends Center
The APOE4 gene, if inherited, increases the risk of Alzheimer’s disease (AD) up to 30-fold, but how it contributes to disease progression at the molecular level is not known. Our lab has recently shown that the clipping of this protein produces a smaller fragment that goes rogue, traffics to the nucleus and may stimulate cell death in the AD brain. Our data suggest a novel role for this molecule and may provide the link between inheriting this gene and the 30-fold risk of dementia it carries when expressed.
Troy Rohn graduated in 1990 from the University of California at Davis with a B.S. in Physiology. He received his Ph.D. in Pharmacology from the University of Washington, Seattle in 1994. His interests include the molecular mechanisms underlying Alzheimer’s disease. Dr. Rohn had several Postdoctoral stints including two-plus years living in Paris, France, one year at Montana State University and two years at UC Irvine at the Institute of Brain Aging and Dementia. He has continued research in Alzheimer’s since his arrival at Boise State University in 2000.
Alejandro “Lejo” Flores, Ph.D.
Associate Professor, Department of Geosciences
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Keith Thiede, Ph.D.
Associate Dean of Research and Graduate Programs, College of Education
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Tim Andersen, Ph.D
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Lindsey Turner, Ph.D.
Research Associate Professor and Director of Initiative for Healthy Schools
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Anthony Ellertson, Ph.D.
Program Director, Gaming and Interactive Mobile Technology (GIMM)
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Cheryl Jorcyk, Ph.D
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